DVT

in Venous Thromboembolism

Applied

Type

Addition

Confidence

75%

Created

Mar 19, 2026

Evidence

1 source

Rationale

The section was updated to include the concept of clinically unsuspected (incidental) DVT, which is a significant clinical entity, especially in pediatric populations as highlighted by the ISTH SSC subcommittee recommendations. This adds a necessary dimension to the clinical presentation section which previously only focused on symptomatic adult DVT. Abbreviations were expanded on first use as per the guidelines.

Evidence

Betensky M et al. Recommendations for standardized definitions, clinical assessment, and future research in pediatric clinically unsuspected venous thromboembolism: Communication from the ISTH SSC subcommittee on pediatric and neonatal thrombosis and hemostasis. J Thromb Haemost. 2022. PMID: 35570328.

Verified source

PubMed DOI

Content Changes

removedadded

* Unilateral swelling, pain, erythema, warmth.
* Homan's sign (calf pain on dorsiflexion) – non-specific.
* Proximal [[deep vein thrombosis (DVT)]] (iliofemoral) → higher [[pulmonary embolism (PE)]] risk.
* Long-term sequelae include post-thrombotic syndrome ([[CVI|PTS]]).

([[CVI|PTS]]) [@kearon2016] [@kahn2014][@kahn2014].
* Clinically unsuspected (incidental) DVT is increasingly recognized, particularly in pediatric and neonatal populations, necessitating standardized definitions and clinical assessment [@betensky2022].

Go to section in textbook Dispute / Submit evidence All updates