Transcutaneous Oxygen Pressure (TcPO₂)

in Vascular Diagnostics and Imaging

Applied

Type

Addition

Confidence

85%

Created

Mar 19, 2026

Evidence

2 sources

Rationale

The section was updated to include the full expansion of the TcPO₂ abbreviation and to integrate high-level evidence (systematic reviews and meta-analyses) regarding its clinical utility. Chuter 2023 provides specific context for the diabetic population, which is a primary use case for TcPO₂, while Zhang 2026 highlights its modern application as a monitoring tool for regenerative medicine interventions.

Evidence

Zhang H et al. Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Therapy for Diabetic Foot Ulcers and Peripheral Artery Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J Foot Ankle Surg. 2026. PMID: 41789620.
Verified source
PubMedDOI
Chuter V et al. Performance of non-invasive bedside vascular testing in the prediction of wound healing or amputation among people with foot ulcers in diabetes: A systematic review. Diabetes Metab Res Rev. 2023. PMID: 37493206.
Verified source
PubMedDOI

Content Changes

* AssessesTranscutaneous oxygen pressure (TcPO₂) assesses skin oxygenation,oxygenation and predicts wound healing.healing potential.
* >50 mmHg = good healing potential.
* <20 mmHg = poor healing potential.potential [@schepers2010] [@conte2019-gvg][@conte2019-gvg].
* In patients with diabetic foot ulcers (DFU), TcPO₂ is a useful bedside predictor of wound healing and amputation risk, although its performance as a standalone tool varies [@chuter2023].
* It is also used to monitor microcirculatory response to advanced therapies, such as mesenchymal stem cell (MSC) therapy [@zhang2026].
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