Transcutaneous Oxygen Pressure (TcPO₂)

in Vascular Diagnostics and Imaging

Applied

Type

Addition

Confidence

80%

Created

Mar 19, 2026

Evidence

2 sources

Rationale

The section was expanded to include recent systematic review evidence regarding the diagnostic performance of TcPO₂ in diabetic populations and its emerging role as a monitoring tool for regenerative therapies. Abbreviations were expanded on first use as required.

Evidence

Zhang H. Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Therapy for Diabetic Foot Ulcers and Peripheral Artery Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J Am Podiatr Med Assoc. 2026. PMID: 41789620.
Verified source
PubMedDOI
Chuter V et al. Performance of non-invasive bedside vascular testing in the prediction of wound healing or amputation among people with foot ulcers in diabetes: A systematic review. Diabet Med. 2023. PMID: 37493206.
Verified source
PubMedDOI

Content Changes

* AssessesTranscutaneous oxygen pressure (TcPO₂) assesses skin oxygenation,oxygenation and predicts wound healing.healing potential.
* >50 mmHg = good healing potential.
* <20 mmHg = poor healing potential. [@schepers2010] [@conte2019-gvg]
* TcPO₂ serves as a bedside predictor for wound healing and amputation risk in patients with diabetes, though its diagnostic performance is variable. [@chuter2023-performance]
* It is also used as a physiological marker to monitor the efficacy of umbilical cord mesenchymal stem cell (UC-MSC) therapy for diabetic foot ulcers (DFU) and peripheral artery disease (PAD). [@zhang2026-safety]
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