Type A Aortic Dissection
Applied
Type
ModificationConfidence
95%
Created
Mar 26, 2026
Evidence
2 sources
Rationale
The integration incorporates the major updates from the 2022 ACC/AHA Aortic Disease guidelines. Key additions include the emphasis on multidisciplinary teams, specific blood pressure targets (SBP < 120 mmHg), and modern surgical techniques like valve-sparing root replacement and the frozen elephant trunk. I also ensured geographic balance by pairing the new US guidelines with the existing ESVS 2025 citation key where appropriate. All abbreviations were expanded on first use as per instructions.
Evidence
Content Changes
removedadded
Type A aortic dissection (TAAD) constitutes a surgical emergency. Without intervention, early mortality is high, driven by aortic rupture, cardiac tamponade, acute aortic regurgitation, coronary malperfusion, or stroke. [@hagan2000] [@trimarchi2005] Current guidelines emphasize that management by a multidisciplinary aortic team in high-volume centers is associated with improved survival [@aha2022-b] [@aha2023-writing] [@esvs2025]. **Clinical Presentation** The classic presentation is sudden, severe "tearing" or "ripping" chest pain radiating to the back. However, presentations vary widely:widely. Clinicians should maintain a high index of suspicion in patients with known genetic predispositions (e.g., Marfan syndrome) or a strong family history of aortic disease [@aha2022-b]: * **Anterior chest pain:** Suggests ascending aortic involvement * **Interscapular pain:** Suggests arch or descending extension * **Syncope:** May indicate tamponade, stroke, or severe hypotension * **Neurologic deficits:** Stroke (arch vessel involvement), paraplegia (spinal cord ischemia) * **Limb ischemia:** Pulse deficits from iliac extension or obstruction * **Abdominal pain:** Visceral malperfusion Physical examination may reveal blood pressure (BP) differential between arms (greater than 20 mmHg), new aortic regurgitation murmur, or signs of tamponade (hypotension, elevated JVP,jugular venous pressure (JVP), muffled heart sounds). **Diagnosis** CTComputed tomography angiography (CTA) is the diagnostic modality of choice—rapid, widely available, and highly sensitive and specific. Findings include intimal flap, true and false lumens, and extent of dissection. Transesophageal echocardiography (TEE) is an important adjunct, particularly for assessing aortic valve involvement, pericardial effusion, and coronary ostia. [@hiratzka2010] [@isselbacher2022] **Surgical Management** Emergent open surgical repair is the standard of care for TypeTAAD. AInitial dissection:medical management focuses on aggressive heart rate and blood pressure control, typically targeting a systolic blood pressure (SBP) < 120 mmHg to reduce aortic wall stress [@aha2022-b] [@aha2023-writing]. * **Ascending aorta replacement:** With or without aortic root replacementreplacement. (BentallIn proceduresuitable ifpatients, valve-sparing root replacement (VSRR) is aneurysmalpreferred orover valvea iscomposite incompetent)graft (Bentall procedure) to avoid long-term anticoagulation [@aha2022-b] [@esvs2025]. * **Hemiarch repair:** Replacement of the lesser curvature of the arch under hypothermic circulatory arrestarrest. * **Total arch replacement:** WhenIndicated when the arch is aneurysmal, torn,contains ora hasprimary entry site;tear, requiresor archis vesselextensively reimplantationdissected. This may involve the "frozen elephant trunk" (FET) technique to facilitate future distal repair [@aha2022-b] [@esvs2025]. Adjunctive measures include antegrade cerebral perfusion during circulatory arrest to reduce neurologic injury. Contemporary registry data and guideline syntheses support operative repair as the default strategy in eligible patients, with outcomes influenced by malperfusion, age, and center experience. [@trimarchi2005] [@isselbacher2022] [@aha2023-writing] **Hybrid and Endovascular Approaches** Selected Type ATAAD dissectionscases may be candidates for hybrid approaches combining open ascending repair with endovascular arch/descending treatment. Purely endovascular Type A repair remains investigational and is limited to highly selected patients who are prohibitive surgical risks. [@isselbacher2022] [@aha2022-b]