Outcomes and Evidence
Applied
Type
ReinforcementConfidence
85%
Created
Mar 26, 2026
Evidence
1 source
Rationale
The section was updated to include the Cralley 2026 study, which is a significant registry-based comparison between Zone 1 REBOA and resuscitative thoracotomy. This addition provides more contemporary evidence to the 'REBOA outcomes' subsection while maintaining the existing cautionary tone regarding observational data and selection bias. Abbreviations (EVTM, RT) were expanded on first use as required.
Evidence
Content Changes
removedadded
<!-- type: evidence --> **Evidence landscape** Most endovascular trauma management (EVTM) outcome data are **observational** (registries, administrative datasets, and single-center series). Interpretation requires attention to indication, timing, comparator selection, and survivorship bias. [@trauma2016-aorta] [@matsumura2020] **resuscitative endovascular balloon occlusion of the aorta (REBOA) outcomes** - Registries demonstrate feasibility and define complication patterns; outcome signals vary by indication and practice environment. [@trauma2016-aorta] - Comparative observational analyses versus resuscitative thoracotomy (RT) show mixed results and are highly selection-dependent.selection-dependent [@brenner2018-survival][@brenner2018-survival]. Recent registry data comparing Zone 1 REBOA to RT for patients in severe hemorrhagic shock suggest potential survival benefits in specific cohorts, though the risk of confounding by indication persists in these non-randomized comparisons [@cralley2026-zone]. **Hybrid/endovascular strategy outcomes (what “success” means)** Beyond survival, meaningful endpoints include: - Time to hemorrhage control - Blood product utilization - Organ failure and ischemic complications (renal/visceral/limb) - Need for fasciotomy or access repair - Limb salvage and functional outcome (especially in extremity/junctional trauma). [@rasmussen2011-vascular] **Why registries remain central** Given case heterogeneity and low event frequency at single centers, multi-institution registries are important for benchmarking, governance, and complication surveillance. [@mani2020] See also: [[Vascular Trauma|Ch. 15]] for extremity injury outcomes and shunt/bypass benchmarks.